ABSTRACT
President Trump mentioned the potential antiviral benefits of hydroxychloroquine as the COVID-19 crisis became evident in the United States. Politics and mass media in the United States have been undergoing a process of partisan polarization over the last 20-30 years. While partisanship has long affected reactions toward news or information, particularly when it comes from an elected official, the situation appears to be worsening in American politics. Even a search for potential cures or useful medication in the face of a public health crisis is hampered by partisanship and polarization.
ABSTRACT
Relapse of infection due to SARS-CoV-2 has been rarely described and there is little guidance regarding the management of such cases in immunocompromised hosts. We present a case of an adolescent female with B-cell acute lymphoblastic leukemia hospitalized multiple times for symptomatic SARS-CoV-2 infection who was safely treated with 2 courses of remdesivir (RDV) and has had no additional readmissions to date. Though additional studies are needed to confirm the safety and efficacy of an additional course of RDV in the setting of relapsed or prolonged severe COVID-19, our observations suggest that a second course of RDV may be considered.